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dnaX [2017-12-07 13:27:14]
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dnaX [2017-12-07 13:27:14]

DNA polymerase III (gamma and tau subunits) part of the clamp-loader complex and the replisome
locus
BSU00190
pI
5.49
mw
62.53 kDa
protein length
563 aa Sequence Blast
gene length
1689 bp Sequence Blast
function
DNA replication
product
DNA polymerase III (gamma and tau subunits)
essential
yes
ec
2.7.7.7
synonyms
dnaH, dna-8132
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • Gene

    Coordinates
    26,814 → 28,505

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Catalyzed reaction/ biological activity

  • Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) (according to Swiss-Prot)
  • required for bacteriophage SPP1 replication [Pubmed|23268446]

    • Structure

  • [PDB|1JR3] (from ''E. coli'', 39% identity) [Pubmed|11525729]

    • [SW|Localization]

  • forms foci [Pubmed|21958350]
  • Nucleoid (Mid-cell) [Pubmed|16479537]

    • Expression and Regulation

    Operons

    genes
    [gene|73D063EDC412F7F28DA27C986ECCCD1C4A1F6618|dnaX]-[gene|9AFCEFE83560B1E2B1FFD7CFD2E4F17FAE137889|yaaK]-[gene|BEBAF1EB53EBB3E7558BB5FE73C418B50000FA29|recR]-[gene|C5127208E7562F09249112240F0BE8C582B2E5AD|yaaL]-[gene|CB5D3A2E5BEE336539BEB2D7C5D9C3A63C78FD01|bofA]
    description
    [Pubmed|22383849]
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    References

  • 16479537,19415803,14757052,12974630,1703271,12466528,20122408,23525462,23268446,21958350,11525729